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Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis

BACKGROUND: Rehabilitation, which is essential for amputees with myoelectric hands, can improve the quality of daily life by remodeling the neuron network. In our study, we aim to develop a cerebral blood perfusion (CBF) single-photon emission computed tomography computer-aided (SPECT-CA) detection...

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Autores principales: Liu, Qiufang, Zheng, Xiujuan, Li, Panli, Xu, Lian, He, Longwen, Mei, Zhao, Zhu, Yinyan, Huang, Gang, Zhong, Chunlong, Song, Shaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006566/
https://www.ncbi.nlm.nih.gov/pubmed/27576313
http://dx.doi.org/10.1186/s12868-016-0294-3
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author Liu, Qiufang
Zheng, Xiujuan
Li, Panli
Xu, Lian
He, Longwen
Mei, Zhao
Zhu, Yinyan
Huang, Gang
Zhong, Chunlong
Song, Shaoli
author_facet Liu, Qiufang
Zheng, Xiujuan
Li, Panli
Xu, Lian
He, Longwen
Mei, Zhao
Zhu, Yinyan
Huang, Gang
Zhong, Chunlong
Song, Shaoli
author_sort Liu, Qiufang
collection PubMed
description BACKGROUND: Rehabilitation, which is essential for amputees with myoelectric hands, can improve the quality of daily life by remodeling the neuron network. In our study, we aim to develop a cerebral blood perfusion (CBF) single-photon emission computed tomography computer-aided (SPECT-CA) detection scheme to automatically locate the brain’s activated regions after rehabilitation. RESULTS: Five participants without forearms (three male, two female, mean age 51 ± 12.89 years, two missing the right side, and three missing the left side) were included in our study. In the clinical assessment, all of the participants received higher scores after training. The results of the SPM analysis indicated that CBF in the precentral gyrus, postcentral gyrus, frontal lobe, temporal lobe and cerebellum was significantly different among the five participants (P < 0.05). Moreover, SPECT-CA showed that the activated brain areas mainly included the precentral gyrus, postcentral gyrus, cerebellum and extensive cerebral cortex. CONCLUSION: Our study demonstrated that the CBF SPECT-CA method can detect the brain blood perfusion changes induced by rehabilitation with high sensitivity and accuracy. This method has great potential for locating the remodeled neuron regions of amputees with myoelectric hands after rehabilitation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12868-016-0294-3) contains supplementary material, which is available to authorized users.
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spelling pubmed-50065662016-09-01 Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis Liu, Qiufang Zheng, Xiujuan Li, Panli Xu, Lian He, Longwen Mei, Zhao Zhu, Yinyan Huang, Gang Zhong, Chunlong Song, Shaoli BMC Neurosci Research Article BACKGROUND: Rehabilitation, which is essential for amputees with myoelectric hands, can improve the quality of daily life by remodeling the neuron network. In our study, we aim to develop a cerebral blood perfusion (CBF) single-photon emission computed tomography computer-aided (SPECT-CA) detection scheme to automatically locate the brain’s activated regions after rehabilitation. RESULTS: Five participants without forearms (three male, two female, mean age 51 ± 12.89 years, two missing the right side, and three missing the left side) were included in our study. In the clinical assessment, all of the participants received higher scores after training. The results of the SPM analysis indicated that CBF in the precentral gyrus, postcentral gyrus, frontal lobe, temporal lobe and cerebellum was significantly different among the five participants (P < 0.05). Moreover, SPECT-CA showed that the activated brain areas mainly included the precentral gyrus, postcentral gyrus, cerebellum and extensive cerebral cortex. CONCLUSION: Our study demonstrated that the CBF SPECT-CA method can detect the brain blood perfusion changes induced by rehabilitation with high sensitivity and accuracy. This method has great potential for locating the remodeled neuron regions of amputees with myoelectric hands after rehabilitation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12868-016-0294-3) contains supplementary material, which is available to authorized users. BioMed Central 2016-08-31 /pmc/articles/PMC5006566/ /pubmed/27576313 http://dx.doi.org/10.1186/s12868-016-0294-3 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Liu, Qiufang
Zheng, Xiujuan
Li, Panli
Xu, Lian
He, Longwen
Mei, Zhao
Zhu, Yinyan
Huang, Gang
Zhong, Chunlong
Song, Shaoli
Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
title Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
title_full Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
title_fullStr Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
title_full_unstemmed Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
title_short Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
title_sort cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a spect computer-aided analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006566/
https://www.ncbi.nlm.nih.gov/pubmed/27576313
http://dx.doi.org/10.1186/s12868-016-0294-3
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