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Modeling Human Leukemia Immunotherapy in Humanized Mice
The currently available human tumor xenograft models permit modeling of human cancers in vivo, but in immunocompromised hosts. Here we report a humanized mouse (hu-mouse) model made by transplantation of human fetal thymic tissue plus hematopoietic stem cells transduced with a leukemia-associated fu...
Autores principales: | Xia, Jinxing, Hu, Zheng, Yoshihara, Satoshi, Li, Yuying, Jin, Chun-Hui, Tan, Shulian, Li, Wei, Chen, Qingfeng, Sykes, Megan, Yang, Yong-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006579/ https://www.ncbi.nlm.nih.gov/pubmed/27394641 http://dx.doi.org/10.1016/j.ebiom.2016.06.028 |
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