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HIV-1 clade C escapes broadly neutralizing autologous antibodies with N332 glycan specificity by distinct mechanisms

The glycan supersite centered on N332 in the V3 base of the HIV-1 envelope (Env) is a target for broadly neutralizing antibodies (bnAbs) such as PGT121 and PGT128. In this study, we examined the basis of resistance of HIV-1 clade C Envs obtained from broadly cross neutralizing (BCN) plasma of an Ind...

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Detalles Bibliográficos
Autores principales:	Deshpande, Suprit, Patil, Shilpa, Kumar, Rajesh, Hermanus, Tandile, Murugavel, Kailapuri G., Srikrishnan, Aylur K., Solomon, Suniti, Morris, Lynn, Bhattacharya, Jayanta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006590/ https://www.ncbi.nlm.nih.gov/pubmed/27576440 http://dx.doi.org/10.1186/s12977-016-0297-2

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