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Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves

Individuals with bicuspid aortic valves (BAV) are at a higher risk of developing thoracic aortic aneurysms (TAA) than patients with trileaflet aortic valves (TAV). The aneurysms associated with BAV most commonly involve the ascending aorta and spare the descending aorta. Smooth muscle cells (SMCs) i...

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Detalles Bibliográficos
Autores principales:	Jiao, Jiao, Xiong, Wei, Wang, Lunchang, Yang, Jiong, Qiu, Ping, Hirai, Hiroyuki, Shao, Lina, Milewicz, Dianna, Chen, Y. Eugene, Yang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006642/ https://www.ncbi.nlm.nih.gov/pubmed/27394642 http://dx.doi.org/10.1016/j.ebiom.2016.06.045

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