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PPARG Post-translational Modifications Regulate Bone Formation and Bone Resorption
The peroxisome proliferator-activated receptor gamma (PPARγ) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. However, clinical use of TZDs has been limit...
Autores principales: | Stechschulte, L.A., Czernik, P.J., Rotter, Z.C., Tausif, F.N., Corzo, C.A., Marciano, D.P., Asteian, A., Zheng, J., Bruning, J.B., Kamenecka, T.M., Rosen, C.J., Griffin, P.R., Lecka-Czernik, B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006645/ https://www.ncbi.nlm.nih.gov/pubmed/27422345 http://dx.doi.org/10.1016/j.ebiom.2016.06.040 |
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