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Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity
RATIONALE: CSL112, human apolipoprotein A-I (apoA-I) reconstituted with phosphatidylcholine, is known to cause a dramatic rise in small high-density lipoprotein (HDL). OBJECTIVE: To explore the mechanisms by which the formation of small HDL particles is induced by CSL112. METHODS AND RESULTS: Infusi...
Autores principales: | Didichenko, Svetlana A., Navdaev, Alexei V., Cukier, Alexandre M.O., Gille, Andreas, Schuetz, Patrick, Spycher, Martin O., Thérond, Patrice, Chapman, M. John, Kontush, Anatol, Wright, Samuel D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006797/ https://www.ncbi.nlm.nih.gov/pubmed/27436846 http://dx.doi.org/10.1161/CIRCRESAHA.116.308685 |
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