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Identification of Peptide Mimics of a Glycan Epitope on the Surface of Parasitic Nematode Larvae

Phage display was used to identify peptide mimics of an immunologically protective nematode glycan (CarLA) by screening a constrained C7C peptide library for ligands that bound to an anti-CarLA mAb (PAB1). Characterisation of these peptide mimotopes revealed functional similarities with an epitope t...

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Detalles Bibliográficos
Autores principales: Umair, Saleh, Deng, Qing, Roberts, Joanna M., Shaw, Richard J., Sutherland, Ian A., Pernthaner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006967/
https://www.ncbi.nlm.nih.gov/pubmed/27579674
http://dx.doi.org/10.1371/journal.pone.0162016

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