Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

Unlike for other retroviruses, only a few host cell factors that aid the replication of foamy viruses (FVs) via interaction with viral structural components are known. Using a yeast-two-hybrid (Y2H) screen with prototype FV (PFV) Gag protein as bait we identified human polo-like kinase 2 (hPLK2), a...

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Detalles Bibliográficos
Autores principales: Zurnic, Irena, Hütter, Sylvia, Rzeha, Ute, Stanke, Nicole, Reh, Juliane, Müllers, Erik, Hamann, Martin V., Kern, Tobias, Gerresheim, Gesche K., Lindel, Fabian, Serrao, Erik, Lesbats, Paul, Engelman, Alan N., Cherepanov, Peter, Lindemann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006980/
https://www.ncbi.nlm.nih.gov/pubmed/27579920
http://dx.doi.org/10.1371/journal.ppat.1005860

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