Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

The natural killer cell receptor NKG2D activates NK cells by engaging one of several ligands (NKG2DLs) belonging to either the MIC or ULBP families. Human cytomegalovirus (HCMV) UL16 and UL142 counteract this activation by retaining NKG2DLs and US18 and US20 act via lysomal degradation but the impor...

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Detalles Bibliográficos
Autores principales: Sturgill, Elizabeth R., Malouli, Daniel, Hansen, Scott G., Burwitz, Benjamin J., Seo, Seongkyung, Schneider, Christine L., Womack, Jennie L., Verweij, Marieke C., Ventura, Abigail B., Bhusari, Amruta, Jeffries, Krystal M., Legasse, Alfred W., Axthelm, Michael K., Hudson, Amy W., Sacha, Jonah B., Picker, Louis J., Früh, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006984/
https://www.ncbi.nlm.nih.gov/pubmed/27580123
http://dx.doi.org/10.1371/journal.ppat.1005868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006984/
https://www.ncbi.nlm.nih.gov/pubmed/27580123
http://dx.doi.org/10.1371/journal.ppat.1005868

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