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Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis

Mycobacterium tuberculosis continues to cause widespread, life-threatening disease. In the last decade, this threat has grown dramatically as multi- and extensively-drug resistant (MDR and XDR) bacteria have spread globally and the number of agents that effectively treat these infections is signific...

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Detalles Bibliográficos
Autores principales: Hajian, Behnoush, Scocchera, Eric, Keshipeddy, Santosh, G-Dayanandan, Narendran, Shoen, Carolyn, Krucinska, Jolanta, Reeve, Stephanie, Cynamon, Michael, Anderson, Amy C., Wright, Dennis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006990/
https://www.ncbi.nlm.nih.gov/pubmed/27580226
http://dx.doi.org/10.1371/journal.pone.0161740