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Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation

MAP kinases of the ERK family are conserved from yeast to humans. Their catalytic activity is dependent on dual phosphorylation of their activation loop’s TEY motif, catalyzed by MAPK kinases (MEKs). Here we studied variants of Mpk1, a yeast orthologue of Erk, which is essential for cell wall integr...

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Detalles Bibliográficos
Autores principales:	Goshen-Lago, Tal, Goldberg-Carp, Anat, Melamed, Dganit, Darlyuk-Saadon, Ilona, Bai, Chen, Ahn, Natalie G., Admon, Arie, Engelberg, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007096/ https://www.ncbi.nlm.nih.gov/pubmed/27413009 http://dx.doi.org/10.1091/mbc.E16-03-0167

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