Cargando…

Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis

During interactions with its mammalian host, the pathogenic yeast Candida albicans is exposed to a range of stresses such as superoxide radicals and cationic fluxes. Unexpectedly, a nonbiased screen of transcription factor deletion mutants revealed that the phosphate-responsive transcription factor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeh, Mélanie A. C., Kastora, Stavroula L., Day, Alison M., Herrero-de-Dios, Carmen M., Tarrant, Emma, Waldron, Kevin J., Banks, A. Peter, Bain, Judith M., Lydall, David, Veal, Elizabeth A., MacCallum, Donna M., Erwig, Lars P., Brown, Alistair J. P., Quinn, Janet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007097/ https://www.ncbi.nlm.nih.gov/pubmed/27385340 http://dx.doi.org/10.1091/mbc.E16-05-0266

Ejemplares similares

Blocking Polyphosphate Mobilization Inhibits Pho4 Activation and Virulence in the Pathogen Candida albicans
por: Ahmed, Yasmin, et al.
Publicado: (2022)

Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation
por: Day, Alison M., et al.
Publicado: (2017)

Sfp1 and Rtg3 reciprocally modulate carbon source‐conditional stress adaptation in the pathogenic yeast Candida albicans
por: Kastora, Stavroula L., et al.
Publicado: (2017)

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs
por: Herrero-de-Dios, Carmen, et al.
Publicado: (2018)

Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen
por: Day, Alison M., et al.
Publicado: (2017)

Non-lytic expulsion/exocytosis of Candida albicans from macrophages
por: Bain, Judith M., et al.
Publicado: (2012)

Macrophage Migration Is Impaired within Candida albicans Biofilms
por: Alonso, Maria F., et al.
Publicado: (2017)

Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans
por: da Silva Dantas, Alessandra, et al.
Publicado: (2015)

Candida albicans infection inhibits macrophage cell division and proliferation
por: Lewis, Leanne E., et al.
Publicado: (2012)

Massive induction of innate immune response to Candida albicans in the kidney in a murine intravenous challenge model
por: MacCallum, Donna M
Publicado: (2009)

Early-Expressed Chemokines Predict Kidney Immunopathology in Experimental Disseminated Candida albicans Infections
por: MacCallum, Donna M., et al.
Publicado: (2009)

Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans
por: Vieira, Neide, et al.
Publicado: (2010)

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans
por: Leach, Michelle D, et al.
Publicado: (2011)

Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney
por: Walker, Louise A., et al.
Publicado: (2009)

The Pho4 transcription factor mediates the response to arsenate and arsenite in Candida albicans
por: Urrialde, Verónica, et al.
Publicado: (2015)

Rab14 Regulates Maturation of Macrophage Phagosomes Containing the Fungal Pathogen Candida albicans and Outcome of the Host-Pathogen Interaction
por: Okai, Blessing, et al.
Publicado: (2015)

Altered Dynamics of Candida albicans Phagocytosis by Macrophages and PMNs When Both Phagocyte Subsets Are Present
por: Rudkin, Fiona M., et al.
Publicado: (2013)

Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans
por: Nicholls, Susan, et al.
Publicado: (2011)

MAPKKK-independent Regulation of the Hog1 Stress-activated Protein Kinase in Candida albicans
por: Cheetham, Jill, et al.
Publicado: (2011)

Identification of a Novel Response Regulator, Crr1, That Is Required for Hydrogen Peroxide Resistance in Candida albicans
por: Bruce, Catherine R., et al.
Publicado: (2011)

Role of the Candida albicans MNN1 gene family in cell wall structure and virulence
por: Bates, Steven, et al.
Publicado: (2013)

Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans
por: Glittenberg, Marcus T., et al.
Publicado: (2011)

Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants
por: Lewis, Leanne E., et al.
Publicado: (2012)

Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions
por: Wagener, Jeanette, et al.
Publicado: (2017)

Feedback Inhibition in the PhoQ/PhoP Signaling System by a Membrane Peptide
por: Lippa, Andrew M., et al.
Publicado: (2009)

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections
por: Mackie, Joanna, et al.
Publicado: (2016)

Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicans
por: Tillmann, Anna T., et al.
Publicado: (2015)

Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation
por: Bain, Judith M., et al.
Publicado: (2014)

The Evolutionary Rewiring of Ubiquitination Targets Has Reprogrammed the Regulation of Carbon Assimilation in the Pathogenic Yeast Candida albicans
por: Sandai, Doblin, et al.
Publicado: (2012)

Osmosensing by the bacterial PhoQ/PhoP two-component system
por: Yuan, Jing, et al.
Publicado: (2017)

Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity
por: Vautier, Simon, et al.
Publicado: (2015)

PHO15 genes of Candida albicans and Candida parapsilosis encode HAD-type phosphatases dephosphorylating 2-phosphoglycolate
por: Kročová, Eliška, et al.
Publicado: (2018)

Impact of changes at the Candida albicans cell surface upon immunogenicity and colonisation in the gastrointestinal tract()
por: Avelar, Gabriela M., et al.
Publicado: (2022)

Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency
por: Kos, Iaroslava, et al.
Publicado: (2016)

Integrative Model of Oxidative Stress Adaptation in the Fungal Pathogen Candida albicans
por: Komalapriya, Chandrasekaran, et al.
Publicado: (2015)

Structural features of PhoX, one of the phosphate-binding proteins from Pho regulon of Xanthomonas citri
por: Pegos, Vanessa R., et al.
Publicado: (2017)

Three Related Enzymes in Candida albicans Achieve Arginine- and Agmatine-Dependent Metabolism That Is Essential for Growth and Fungal Virulence
por: Schaefer, Katja, et al.
Publicado: (2020)

Correction for Sandai et al., The Evolutionary Rewiring of Ubiquitination Targets Has Reprogrammed the Regulation of Carbon Assimilation in the Pathogenic Yeast Candida albicans
por: Sandai, Doblin, et al.
Publicado: (2015)

Virulence and Stress Responses of Shigella flexneri Regulated by PhoP/PhoQ
por: Lin, Zhiwei, et al.
Publicado: (2018)

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling
por: Pradhan, Arnab, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_13e5am85ec22k4lrlg05opvbbv