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The mammalian dynein/dynactin complex is a strong opponent to kinesin in a tug-of-war competition
Kinesin and dynein motors transport intracellular cargos bidirectionally by pulling them in opposite directions along microtubules, through a process frequently described as a ‘tug of war’. While kinesin produces a 6 pN force, mammalian dynein was found to be a surprisingly weak motor (0.5–1.5 pN) i...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007201/ https://www.ncbi.nlm.nih.gov/pubmed/27454819 http://dx.doi.org/10.1038/ncb3393 |