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The mammalian dynein/dynactin complex is a strong opponent to kinesin in a tug-of-war competition

Kinesin and dynein motors transport intracellular cargos bidirectionally by pulling them in opposite directions along microtubules, through a process frequently described as a ‘tug of war’. While kinesin produces a 6 pN force, mammalian dynein was found to be a surprisingly weak motor (0.5–1.5 pN) i...

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Detalles Bibliográficos
Autores principales:	Belyy, Vladislav, Schlager, Max A., Foster, Helen, Reimer, Armando E., Carter, Andrew P., Yildiz, Ahmet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007201/ https://www.ncbi.nlm.nih.gov/pubmed/27454819 http://dx.doi.org/10.1038/ncb3393

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