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A Comparative Evaluation of Hydroxycamptothecin Drug Nanorods With and Without Methotrexate Prodrug Functionalization for Drug Delivery

We developed a novel self-targeted multi-drug co-delivery system based on rod-shaped 10-hydroxycamptothecin (CPT) nanoanticancer drug (CPT NRs) followed by a surface functionalization with self-targeting PEGylated lipid-conjugated methotrexate (MTX) pro-anticancer drug. The self-targeting effect and...

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Detalles Bibliográficos
Autores principales:	Guo, Fuqiang, Fan, Zhongxiong, Yang, Jinbin, Li, Yang, Wang, Yange, Zhao, Hai, Xie, Liya, Hou, Zhenqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2016
Materias:	Nano Express
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007229/ https://www.ncbi.nlm.nih.gov/pubmed/27581601 http://dx.doi.org/10.1186/s11671-016-1599-y

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