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Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia
Sustained hypoxia over several hours induces a progressive rise in pulmonary artery systolic pressure (PASP). Administration of intravenous iron immediately prior to the hypoxia exposure abrogates this effect, suggesting that manipulation of iron stores may modify hypoxia-induced pulmonary hypertens...
Autores principales: | Bart, Nicole K., Curtis, M. Kate, Cheng, Hung-Yuan, Hungerford, Sara L., McLaren, Ross, Petousi, Nayia, Dorrington, Keith L., Robbins, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007321/ https://www.ncbi.nlm.nih.gov/pubmed/27418684 http://dx.doi.org/10.1152/japplphysiol.00032.2016 |
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