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Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression

Mitochondrial uncoupling protein 2 (UCP2) has been well characterized to control the production of reactive oxygen species (ROS) and astrocytes are the major cells responsible for the ROS production and the inflammatory responses in the brain. However, the function of UCP2 in astrocytes and the cont...

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Detalles Bibliográficos
Autores principales: Du, Ren-Hong, Wu, Fang-Fang, Lu, Ming, Shu, Xiao-dong, Ding, Jian-Hua, Wu, Guangyu, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007434/
https://www.ncbi.nlm.nih.gov/pubmed/27566281
http://dx.doi.org/10.1016/j.redox.2016.08.006