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The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease

BACKGROUND: Mitochondrial dysfunction and bioenergetic stress play an important role in the etiology of alcoholic liver disease. Previous studies from our laboratory show that the primary methyl donor S-Adenosylmethionine (SAM) minimizes alcohol-induced disruptions in several mitochondrial functions...

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Detalles Bibliográficos
Autores principales:	King, Adrienne L., Mantena, Sudheer K., Andringa, Kelly K., Millender-Swain, Telisha, Dunham-Snary, Kimberly J., Oliva, Claudia R., Griguer, Corinne E., Bailey, Shannon M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007436/ https://www.ncbi.nlm.nih.gov/pubmed/27566282 http://dx.doi.org/10.1016/j.redox.2016.08.005

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