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TNIK inhibition abrogates colorectal cancer stemness

Canonical Wnt/β-catenin signalling is essential for maintaining intestinal stem cells, and its constitutive activation has been implicated in colorectal carcinogenesis. We and others have previously identified Traf2- and Nck-interacting kinase (TNIK) as an essential regulatory component of the T-cel...

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Detalles Bibliográficos
Autores principales:	Masuda, Mari, Uno, Yuko, Ohbayashi, Naomi, Ohata, Hirokazu, Mimata, Ayako, Kukimoto-Niino, Mutsuko, Moriyama, Hideki, Kashimoto, Shigeki, Inoue, Tomoko, Goto, Naoko, Okamoto, Koji, Shirouzu, Mikako, Sawa, Masaaki, Yamada, Tesshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007443/ https://www.ncbi.nlm.nih.gov/pubmed/27562646 http://dx.doi.org/10.1038/ncomms12586

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