Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo

Burkholderia cenocepacia, an opportunistic respiratory pathogen particularly relevant for cystic fibrosis patients, is difficult to eradicate due to its high level of resistance to most clinically relevant antimicrobials. Consequently, the discovery of new antimicrobials as well as molecules capable...

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Detalles Bibliográficos
Autores principales: Scoffone, Viola C., Chiarelli, Laurent R., Makarov, Vadim, Brackman, Gilles, Israyilova, Aygun, Azzalin, Alberto, Forneris, Federico, Riabova, Olga, Savina, Svetlana, Coenye, Tom, Riccardi, Giovanna, Buroni, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007513/
https://www.ncbi.nlm.nih.gov/pubmed/27580679
http://dx.doi.org/10.1038/srep32487

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