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Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae

The N(1) methylation of adenine at position 58 (m(1)A58) of tRNA is an important post-transcriptional modification, which is vital for maintaining the stability of the initiator methionine tRNA(i)(Met). In eukaryotes, this modification is performed by the TRM6-TRM61 holoenzyme. To understand the mol...

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Detalles Bibliográficos
Autores principales:	Wang, Mingxing, Zhu, Yuwei, Wang, Chongyuan, Fan, Xiaojiao, Jiang, Xuguang, Ebrahimi, Mohammad, Qiao, Zhi, Niu, Liwen, Teng, Maikun, Li, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007650/ https://www.ncbi.nlm.nih.gov/pubmed/27582183 http://dx.doi.org/10.1038/srep32562

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