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The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation
The major human pathogen Streptococcus pneumoniae is a leading cause of disease and death worldwide. Pneumococcal biofilm formation within the nasopharynx leads to long-term colonization and persistence within the host. We have previously demonstrated that the capsular surface-associated pneumococca...
Autores principales: | Schulte, Tim, Mikaelsson, Cecilia, Beaussart, Audrey, Kikhney, Alexey, Deshmukh, Maya, Wolniak, Sebastian, Pathak, Anuj, Ebel, Christine, Löfling, Jonas, Fogolari, Federico, Henriques-Normark, Birgitta, Dufrêne, Yves F., Svergun, Dmitri, Nygren, Per-Åke, Achour, Adnane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007671/ https://www.ncbi.nlm.nih.gov/pubmed/27582320 http://dx.doi.org/10.1038/srep32371 |
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