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Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro
BACKGROUND: Multiple myeloma is an incurable complex disease characterized by clonal proliferation of malignant plasma cells in a hypoxic bone marrow environment. Hypoxia-dependent erythropoietin (EPO)-receptor (EPOR) signaling is central in various cancers, but the relevance of EPOR signaling in mu...
Autores principales: | Våtsveen, Thea Kristin, Sponaas, Anne-Marit, Tian, Erming, Zhang, Qing, Misund, Kristine, Sundan, Anders, Børset, Magne, Waage, Anders, Brede, Gaute |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007700/ https://www.ncbi.nlm.nih.gov/pubmed/27581518 http://dx.doi.org/10.1186/s13045-016-0306-x |
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