Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is associated with inflammatory response but it is unknown whether it is associated with alterations in NNMT activity and MNA plasma concentration. Here we examined changes in NNMT-MNA pathway in PAH in rats and humans. METHODS: PAH in rats was induc...

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Detalles Bibliográficos
Autores principales: Fedorowicz, Andrzej, Mateuszuk, Łukasz, Kopec, Grzegorz, Skórka, Tomasz, Kutryb-Zając, Barbara, Zakrzewska, Agnieszka, Walczak, Maria, Jakubowski, Andrzej, Łomnicka, Magdalena, Słomińska, Ewa, Chlopicki, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007701/
https://www.ncbi.nlm.nih.gov/pubmed/27581040
http://dx.doi.org/10.1186/s12931-016-0423-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007701/
https://www.ncbi.nlm.nih.gov/pubmed/27581040
http://dx.doi.org/10.1186/s12931-016-0423-7

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