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Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension
BACKGROUND: Pulmonary arterial hypertension (PAH) is associated with inflammatory response but it is unknown whether it is associated with alterations in NNMT activity and MNA plasma concentration. Here we examined changes in NNMT-MNA pathway in PAH in rats and humans. METHODS: PAH in rats was induc...
Autores principales: | Fedorowicz, Andrzej, Mateuszuk, Łukasz, Kopec, Grzegorz, Skórka, Tomasz, Kutryb-Zając, Barbara, Zakrzewska, Agnieszka, Walczak, Maria, Jakubowski, Andrzej, Łomnicka, Magdalena, Słomińska, Ewa, Chlopicki, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007701/ https://www.ncbi.nlm.nih.gov/pubmed/27581040 http://dx.doi.org/10.1186/s12931-016-0423-7 |
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