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How MCM loading and spreading specify eukaryotic DNA replication initiation sites

DNA replication origins strikingly differ between eukaryotic species and cell types. Origins are localized and can be highly efficient in budding yeast, are randomly located in early fly and frog embryos, which do not transcribe their genomes, and are clustered in broad (10-100 kb) non-transcribed z...

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Detalles Bibliográficos
Autor principal:	Hyrien, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007759/ https://www.ncbi.nlm.nih.gov/pubmed/27635237 http://dx.doi.org/10.12688/f1000research.9008.1

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