Mutagenic consequences of cytosine alterations site-specifically embedded in the human genome

INTRODUCTION: Cytosine residues in CpG dinucleotides often undergo various types of modification, such as methylation, deamination, and halogenation. These types of modifications can be pro-mutagenic and can contribute to the formation of mutational hotspots in cells. To analyze mutations induced by...

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Detalles Bibliográficos
Autores principales: Sassa, Akira, Kanemaru, Yuki, Kamoshita, Nagisa, Honma, Masamitsu, Yasui, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007816/
https://www.ncbi.nlm.nih.gov/pubmed/27588157
http://dx.doi.org/10.1186/s41021-016-0045-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007816/
https://www.ncbi.nlm.nih.gov/pubmed/27588157
http://dx.doi.org/10.1186/s41021-016-0045-9

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