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Mutagenic consequences of cytosine alterations site-specifically embedded in the human genome
INTRODUCTION: Cytosine residues in CpG dinucleotides often undergo various types of modification, such as methylation, deamination, and halogenation. These types of modifications can be pro-mutagenic and can contribute to the formation of mutational hotspots in cells. To analyze mutations induced by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007816/ https://www.ncbi.nlm.nih.gov/pubmed/27588157 http://dx.doi.org/10.1186/s41021-016-0045-9 |