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The evolutionally-conserved function of group B1 Sox family members confers the unique role of Sox2 in mouse ES cells

BACKGROUND: In mouse ES cells, the function of Sox2 is essential for the maintenance of pluripotency. Since the Sox-family of transcription factors are well conserved in the animal kingdom, addressing the evolutionary origin of Sox2 function in pluripotent stem cells is intriguing from the perspecti...

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Detalles Bibliográficos
Autores principales:	Niwa, Hitoshi, Nakamura, Akira, Urata, Makoto, Shirae-Kurabayashi, Maki, Kuraku, Shigehiro, Russell, Steven, Ohtsuka, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007870/ https://www.ncbi.nlm.nih.gov/pubmed/27582319 http://dx.doi.org/10.1186/s12862-016-0755-4

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