Promoter hypermethylation of HS3ST2, SEPTIN9 and SLIT2 combined with FGFR3 mutations as a sensitive/specific urinary assay for diagnosis and surveillance in patients with low or high-risk non-muscle-invasive bladder cancer

BACKGROUND: Non-muscle-invasive bladder cancer (NMIBC) is a high incidence form of bladder cancer (BCa), where genetic and epigenetic alterations occur frequently. We assessed the performance of associating a FGFR3 mutation assay and a DNA methylation analysis to improve bladder cancer detection and...

Descripción completa

Detalles Bibliográficos
Autores principales: Roperch, Jean-Pierre, Grandchamp, Bernard, Desgrandchamps, François, Mongiat-Artus, Pierre, Ravery, Vincent, Ouzaid, Idir, Roupret, Morgan, Phe, Véronique, Ciofu, Calin, Tubach, Florence, Cussenot, Olivier, Incitti, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007990/
https://www.ncbi.nlm.nih.gov/pubmed/27586786
http://dx.doi.org/10.1186/s12885-016-2748-5

Ejemplares similares

Ejemplares similares