Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers

Cell fate in response to an aberrant mitosis is governed by two competing networks: the spindle assembly checkpoint (SAC) and the intrinsic apoptosis pathway. The mechanistic interplay between these two networks is obscured by functional redundancy and the ability of cells to die either in mitosis o...

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Detalles Bibliográficos
Autores principales: Bennett, Ailsa, Sloss, Olivia, Topham, Caroline, Nelson, Louisa, Tighe, Anthony, Taylor, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008013/
https://www.ncbi.nlm.nih.gov/pubmed/27512141
http://dx.doi.org/10.1098/rsob.160134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008013/
https://www.ncbi.nlm.nih.gov/pubmed/27512141
http://dx.doi.org/10.1098/rsob.160134

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