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Structure-Activity Relationships of the Human Immunodeficiency Virus Type 1 Maturation Inhibitor PF-46396

HIV-1 maturation inhibitors are a novel class of antiretroviral compounds that consist of two structurally distinct chemical classes: betulinic acid derivatives and the pyridone-based compound PF-46396. It is currently believed that both classes act by similar modes of action to generate aberrant no...

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Detalles Bibliográficos
Autores principales:	Murgatroyd, Christopher, Pirrie, Lisa, Tran, Fanny, Smith, Terry K., Westwood, Nicholas J., Adamson, Catherine S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Vaccines and Antiviral Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008107/ https://www.ncbi.nlm.nih.gov/pubmed/27384665 http://dx.doi.org/10.1128/JVI.01075-16

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