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When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest

Living kidney transplantation offers the best treatment in terms of life‐expectancy and quality of life for those with end‐stage renal disease. The long‐term risks of living donor nephrectomy, although real, are very small, with evidence of good medium‐term outcomes. Who should be entitled to donate...

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Detalles Bibliográficos
Autores principales: Bailey, Phillippa, Huxtable, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008185/
https://www.ncbi.nlm.nih.gov/pubmed/26194324
http://dx.doi.org/10.1111/bioe.12177
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author Bailey, Phillippa
Huxtable, Richard
author_facet Bailey, Phillippa
Huxtable, Richard
author_sort Bailey, Phillippa
collection PubMed
description Living kidney transplantation offers the best treatment in terms of life‐expectancy and quality of life for those with end‐stage renal disease. The long‐term risks of living donor nephrectomy, although real, are very small, with evidence of good medium‐term outcomes. Who should be entitled to donate, and in which circumstances, is nevertheless a live question. We explore the ethical dimensions of a request by an individual to donate both of their kidneys during life: ‘dual living kidney donation’. Our ethical analysis is tethered to a hypothetical case study in which a father asks to donate a kidney to each of his twin boys. We explore the autonomy of the protagonists, alongside different dimensions of the public interest, such as the need to protect not only the recipients, but also the donor and even the wider community. Whilst acknowledging objections to ‘dual‐donation’, not least by reference to the harms that the donor might be expected to endure, we suggest there is a prima facie case for permitting this, provided that both donor and recipients are willing and that due attention is paid to such considerations as the autonomy and welfare of all parties, as well as to the wider ramifications of acting on such a request. We argue for broader interpretations of the concepts of autonomy and welfare, recognizing the importance of relationships and the relevance of more than merely physical well‐being. Equipped with such a holistic assessment, we suggest there is a prima facie case for allowing ‘dual living kidney donation’.
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spelling pubmed-50081852016-09-16 When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest Bailey, Phillippa Huxtable, Richard Bioethics Original Articles Living kidney transplantation offers the best treatment in terms of life‐expectancy and quality of life for those with end‐stage renal disease. The long‐term risks of living donor nephrectomy, although real, are very small, with evidence of good medium‐term outcomes. Who should be entitled to donate, and in which circumstances, is nevertheless a live question. We explore the ethical dimensions of a request by an individual to donate both of their kidneys during life: ‘dual living kidney donation’. Our ethical analysis is tethered to a hypothetical case study in which a father asks to donate a kidney to each of his twin boys. We explore the autonomy of the protagonists, alongside different dimensions of the public interest, such as the need to protect not only the recipients, but also the donor and even the wider community. Whilst acknowledging objections to ‘dual‐donation’, not least by reference to the harms that the donor might be expected to endure, we suggest there is a prima facie case for permitting this, provided that both donor and recipients are willing and that due attention is paid to such considerations as the autonomy and welfare of all parties, as well as to the wider ramifications of acting on such a request. We argue for broader interpretations of the concepts of autonomy and welfare, recognizing the importance of relationships and the relevance of more than merely physical well‐being. Equipped with such a holistic assessment, we suggest there is a prima facie case for allowing ‘dual living kidney donation’. John Wiley and Sons Inc. 2015-07-21 2016-02 /pmc/articles/PMC5008185/ /pubmed/26194324 http://dx.doi.org/10.1111/bioe.12177 Text en © 2015 The Authors. Bioethics Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Bailey, Phillippa
Huxtable, Richard
When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest
title When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest
title_full When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest
title_fullStr When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest
title_full_unstemmed When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest
title_short When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest
title_sort when opportunity knocks twice: dual living kidney donation, autonomy and the public interest
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008185/
https://www.ncbi.nlm.nih.gov/pubmed/26194324
http://dx.doi.org/10.1111/bioe.12177
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