Cerebellar output controls generalized spike‐and‐wave discharge occurrence

OBJECTIVE: Disrupting thalamocortical activity patterns has proven to be a promising approach to stop generalized spike‐and‐wave discharges (GSWDs) characteristic of absence seizures. Here, we investigated to what extent modulation of neuronal firing in cerebellar nuclei (CN), which are anatomically...

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Detalles Bibliográficos
Autores principales: Kros, Lieke, Eelkman Rooda, Oscar H. J., Spanke, Jochen K., Alva, Parimala, van Dongen, Marijn N., Karapatis, Athanasios, Tolner, Else A., Strydis, Christos, Davey, Neil, Winkelman, Beerend H. J., Negrello, Mario, Serdijn, Wouter A., Steuber, Volker, van den Maagdenberg, Arn M. J. M., De Zeeuw, Chris I., Hoebeek, Freek E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008217/
https://www.ncbi.nlm.nih.gov/pubmed/25762286
http://dx.doi.org/10.1002/ana.24399

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