Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

In oncolytic virotherapy, the ability of the virus to activate the immune system is a key attribute with regard to long-term antitumor effects. Vaccinia viruses bear one of the strongest oncolytic activities among all oncolytic viruses. However, its capacity for stimulation of antitumor immunity is...

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Detalles Bibliográficos
Autores principales: Hirvinen, Mari, Capasso, Cristian, Guse, Kilian, Garofalo, Mariangela, Vitale, Andrea, Ahonen, Marko, Kuryk, Lukasz, Vähä-Koskela, Markus, Hemminki, Akseli, Fortino, Vittorio, Greco, Dario, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008257/
https://www.ncbi.nlm.nih.gov/pubmed/27626058
http://dx.doi.org/10.1038/mto.2016.2

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