Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma

Osteosarcoma is the most common primary bone malignancy affecting children and adolescents. Although several genetic predisposing conditions have been associated with osteosarcoma, our understanding of its pathobiology is rather limited. Here we show that, first, an imprinting defect at human 14q32-...

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Detalles Bibliográficos
Autores principales: Shu, Jingmin, Li, Lihua, Sarver, Anne E., Pope, Emily A., Varshney, Jyotika, Thayanithy, Venugopal, Spector, Logan, Largaespada, David A., Steer, Clifford J., Subramanian, Subbaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008286/
https://www.ncbi.nlm.nih.gov/pubmed/26802029
http://dx.doi.org/10.18632/oncotarget.6965

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