Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Medullary thyroid carcinomas (MTCs) exhibit telomerase activation in strong association with shorter patient survival. To understand the background of telomerase activation we quantified TERT copy numbers and TERT promoter methylation in 42 MTCs and normal thyroid references. Gain of TERT was demons...

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Detalles Bibliográficos
Autores principales: Wang, Na, Kjellin, Hanna, Sofiadis, Anastasios, Fotouhi, Omid, Juhlin, C. Christofer, Bäckdahl, Martin, Zedenius, Jan, Xu, Dawei, Lehtiö, Janne, Larsson, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008288/
https://www.ncbi.nlm.nih.gov/pubmed/26870890
http://dx.doi.org/10.18632/oncotarget.7237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008288/
https://www.ncbi.nlm.nih.gov/pubmed/26870890
http://dx.doi.org/10.18632/oncotarget.7237

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