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Knockdown of Golgi phosphoprotein 2 inhibits hepatocellular carcinoma cell proliferation and motility

Golgi phosphoprotein 2 (GP73) is highly expressed in hepatocellular carcinoma (HCC) cells, where it serves as a biomarker and indicator of disease progression. We used MTS assays, anchorage-independent cell colony formation assays and a xenograft tumor model to show that GP73-specific siRNAs inhibit...

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Detalles Bibliográficos
Autores principales: Liu, Yiming, Zhang, Xiaodi, Sun, Ting, Jiang, Junchang, Li, Ying, Chen, Mingliang, Wei, Zhen, Jiang, Weiqin, Zhou, Linfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008294/
https://www.ncbi.nlm.nih.gov/pubmed/26870893
http://dx.doi.org/10.18632/oncotarget.7271