TNFSF10/TRAIL regulates human T4 effector memory lymphocyte radiosensitivity and predicts radiation-induced acute and subacute dermatitis

Sensitivity of T4 effector-memory (T4EM) lymphocytes to radiation-induced apoptosis shows heritability compatible with a Mendelian mode of transmission. Using gene expression studies and flow cytometry, we show a higher TNF-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) mRNA level and a higher le...

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Detalles Bibliográficos
Autores principales: Baijer, Jan, Déchamps, Nathalie, Perdry, Hervé, Morales, Pablo, Kerns, Sarah, Vasilescu, Alexandre, Baulande, Sylvain, Azria, David, Roméo, Paul Henri, Schmitz, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008295/
https://www.ncbi.nlm.nih.gov/pubmed/26982083
http://dx.doi.org/10.18632/oncotarget.7893

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