APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis

Despite the fact that the epidermal growth factor (EGF) family member ERBB3 (HER3) is deregulated in many cancers, the list of ERBB3-interacting partners remains limited. Here, we report that the Apaf-1-interacting protein (APIP) stimulates heregulin-β1 (HRG-β1)/ERBB3-driven cell proliferation and t...

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Detalles Bibliográficos
Autores principales: Hong, Se-Hoon, Lee, Won Jae, Kim, Young Doo, Kim, Hyunjoo, Jeon, Young-Jun, Lim, Bitna, Cho, Dong-Hyung, Heo, Won Do, Yang, Doo-Hyun, Kim, Chan-Young, Yang, Han-Kwang, Yang, Jin Kuk, Jung, Yong-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008309/
https://www.ncbi.nlm.nih.gov/pubmed/26942872
http://dx.doi.org/10.18632/oncotarget.7802

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