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Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia
Both preclinical and clinical investigations suggest that Notch signalling is critical for the development of many cancers and for their response to chemotherapy. We previously showed that Notch inhibition abrogates stromal-induced chemoresistance in lymphoid neoplasms. However, the role of Notch in...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008317/ https://www.ncbi.nlm.nih.gov/pubmed/26967055 http://dx.doi.org/10.18632/oncotarget.7964 |