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Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia

Both preclinical and clinical investigations suggest that Notch signalling is critical for the development of many cancers and for their response to chemotherapy. We previously showed that Notch inhibition abrogates stromal-induced chemoresistance in lymphoid neoplasms. However, the role of Notch in...

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Detalles Bibliográficos
Autores principales: Kamga, Paul Takam, Bassi, Giulio, Cassaro, Adriana, Midolo, Martina, Di Trapani, Mariano, Gatti, Alessandro, Carusone, Roberta, Resci, Federica, Perbellini, Omar, Gottardi, Michele, Bonifacio, Massimiliano, Kamdje, Armel Hervé Nwabo, Ambrosetti, Achille, Krampera, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008317/
https://www.ncbi.nlm.nih.gov/pubmed/26967055
http://dx.doi.org/10.18632/oncotarget.7964

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