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Knock-down of Hdj2/DNAJA1 co-chaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells

The chaperone system based on Hsp70 and proteins of the DnaJ family is known to protect tumor cells from a variety of cytotoxic factors, including anti-tumor therapy. To analyze whether this also functions in a highly malignant brain tumor, we knocked down the expression of Hsp70 (HSPA1A) and its tw...

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Detalles Bibliográficos
Autores principales:	Meshalkina, Darya A., Shevtsov, Maxim A., Dobrodumov, Anatoliy V., Komarova, Elena Y., Voronkina, Irina V., Lazarev, Vladimir F., Margulis, Boris A., Guzhova, Irina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008343/ https://www.ncbi.nlm.nih.gov/pubmed/26959111 http://dx.doi.org/10.18632/oncotarget.7872

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