Key roles of necroptotic factors in promoting tumor growth

Necroptotic factors are generally assumed to play a positive role in tumor therapy by eliminating damaged tumor cells. Here we show that, contrary to expectation, necroptotic factors RIPK1, RIPK3, and MLKL promote tumor growth. We demonstrate that genetic knockout of necroptotic genes RIPK1, RIPK3,...

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Detalles Bibliográficos
Autores principales: Liu, Xinjian, Zhou, Min, Mei, Ling, Ruan, Jiaying, Hu, Qian, Peng, Jing, Su, Hang, Liao, Hong, Liu, Shanling, Liu, WeiPing, Wang, He, Huang, Qian, Li, Fang, Li, Chuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008357/
https://www.ncbi.nlm.nih.gov/pubmed/26959742
http://dx.doi.org/10.18632/oncotarget.7924

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