Cargando…

miR-101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma

Gallbladder cancer (GBC), the most common malignancy of the bile duct, is highly aggressive and has an extremely poor prognosis, which is a result of early metastasis. As it is regulated being at multiple levels, the metastatic cascade in GBC is complex. Recent evidence suggests that microRNAs (miRN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bao, Run-Fa, Shu, Yi-Jun, Hu, Yun-Ping, Wang, Xu-An, Zhang, Fei, Liang, Hai-Bin, Ye, Yuan-Yuan, Li, Huai-Feng, Xiang, Shan-Shan, Weng, Hao, Cao, Yang, Wu, Xiang-Song, Li, Mao-Lan, Wu, Wen-guang, Zhang, Yi-Jian, Jiang, Lin, Dong, Qian, Liu, Ying-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008364/ https://www.ncbi.nlm.nih.gov/pubmed/26968949 http://dx.doi.org/10.18632/oncotarget.7970

Ejemplares similares

Baicalein Inhibits Progression of Gallbladder Cancer Cells by Downregulating ZFX
por: Liu, Tian-Yu, et al.
Publicado: (2015)

MicroRNA-29c-5p suppresses gallbladder carcinoma progression by directly targeting CPEB4 and inhibiting the MAPK pathway
por: Shu, Yi-Jun, et al.
Publicado: (2017)

Cordycepin Induces S Phase Arrest and Apoptosis in Human Gallbladder Cancer Cells
por: Wang, Xu-An, et al.
Publicado: (2014)

Clinical and prognostic significance of preoperative plasma hyperfibrinogenemia in gallbladder cancer patients following surgical resection: a retrospective and in vitro study
por: Shu, Yi-Jun, et al.
Publicado: (2014)

Schisandrin B Induces Apoptosis and Cell Cycle Arrest of Gallbladder Cancer Cells
por: Xiang, Shan-Shan, et al.
Publicado: (2014)

Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells
por: Li, Huai-Feng, et al.
Publicado: (2015)

Ursolic acid induces cell cycle arrest and apoptosis of gallbladder carcinoma cells
por: Weng, Hao, et al.
Publicado: (2014)

Correction: Xiang, S., et al. Schisandrin B Induces Apoptosis and Cell Cycle Arrest of Gallbladder Cancer Cells. Molecules 2014, 19, 13235–13250
por: Xiang, Shan-Shan, et al.
Publicado: (2016)

SPOCK1 as a potential cancer prognostic marker promotes the proliferation and metastasis of gallbladder cancer cells by activating the PI3K/AKT pathway
por: Shu, Yi-Jun, et al.
Publicado: (2015)

Homoharringtonine enhances the effect of imatinib on chronic myelogenous leukemia cells by downregulating ZFX
por: Wu, Jingjing, et al.
Publicado: (2019)

Influence of miR-101 on proliferation of liver cancer cells through the MAPK/ERK signaling pathway
por: Meng, Xuan, et al.
Publicado: (2020)

Triptolide Induces S Phase Arrest and Apoptosis in Gallbladder Cancer Cells
por: Hu, Yun-Ping, et al.
Publicado: (2014)

ZFX is a Strong Predictor of Poor Prognosis in Renal Cell Carcinoma
por: Li, Changying, et al.
Publicado: (2015)

MicroRNA-30a-5p inhibits gallbladder cancer cell proliferation, migration and metastasis by targeting E2F7
por: Ye, Yuan-Yuan, et al.
Publicado: (2018)

Development and Validation of a Prognostic Nomogram Based on the Systemic Immune-Inflammation Index for Resectable Gallbladder Cancer to Predict Survival and Chemotherapy Benefit
por: Li, Lin, et al.
Publicado: (2021)

SLC25A22 promotes proliferation and metastasis by activating MAPK/ERK pathway in gallbladder cancer
por: Du, Pengcheng, et al.
Publicado: (2019)

Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways
por: Wang, Wenbo, et al.
Publicado: (2016)

Recurrent ZFX mutations in human sporadic parathyroid adenomas
por: Soong, Chen-Pang, et al.
Publicado: (2014)

Recurrent ZFX mutations in human sporadic parathyroid adenomas
por: Soong, Chen-Pang, et al.
Publicado: (2014)

The Use of RNAi Technology to Interfere with Zfx Gene Increases the Male Rates of Red Deer (Cervus elaphus) Offspring
por: Wei, Limin, et al.
Publicado: (2020)

The Zfx gene is expressed in human gliomas and is important in the proliferation and apoptosis of the human malignant glioma cell line U251
por: Zhou, Youxin, et al.
Publicado: (2011)

Improved long‐term outcomes after innovative preoperative evaluation and conception of precise surgery for gallbladder cancer
por: Jia, Zi‐Yao, et al.
Publicado: (2023)

LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis
por: Hu, Yun-ping, et al.
Publicado: (2019)

ZFX Controls the Self-Renewal of Human Embryonic Stem Cells
por: Harel, Sivan, et al.
Publicado: (2012)

Sex identification using ZFX and ZFY genes in leopard cats (Prionailurus bengalensis euptilurus) in Korea
por: SEOK, Seong Hoon, et al.
Publicado: (2019)

Correction to: LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis
por: Hu, Yun-ping, et al.
Publicado: (2021)

Polydatin prevents bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β/Smad/ERK signaling pathway
por: Liu, Yan-Lu, et al.
Publicado: (2020)

A conserved ZFX/WNT3 axis modulates the growth and imatinib response of chronic myeloid leukemia stem/progenitor cells
por: Zhang, Xiuyan, et al.
Publicado: (2023)

TSG101 and PEG10 are prognostic markers in squamous cell/adenosquamous carcinomas and adenocarcinoma of the gallbladder
por: LIU, ZIRU, et al.
Publicado: (2014)

miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma
por: Jin, Yun-Peng, et al.
Publicado: (2018)

The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation
por: Smith-Raska, Matthew R., et al.
Publicado: (2018)

Differential Expression Profile of ZFX Variants Discriminates Breast Cancer Subtypes
por: Pourkeramati, Fatemeh, et al.
Publicado: (2019)

The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR
por: Zhao, Shuai, et al.
Publicado: (2016)

RKIP suppresses the influenza A virus-induced airway inflammatory response via the ERK/MAPK pathway
por: Ye, Jing-Jing, et al.
Publicado: (2022)

Dahuang Zhechong Pills Suppress Silicosis Fibrosis Progression via p38 MAPK/TGF-β1/Smad Pathway In Vitro
por: Wu, Li-Juan, et al.
Publicado: (2021)

HSV-TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK
por: Yi, Quan-Yong, et al.
Publicado: (2018)

Case report: A de novo ERBB3 mutation develops in a gallbladder cancer patient carrying BRCA1 mutation after effective treatment with olaparib
por: Yang, Jing-Xiao, et al.
Publicado: (2023)

Leptin induces osteocalcin expression in ATDC5 cells through activation of the MAPK-ERK1/2 signaling pathway
por: Han, Yingchao, et al.
Publicado: (2016)

Effect of Over-Expression of Zinc-Finger Protein (ZFX) on Self-Renewal and Drug-Resistance of Hepatocellular Carcinoma
por: Zhang, Shuhong, et al.
Publicado: (2016)

Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK‐ERK signalling pathway in vivo and in vitro
por: Han, Ying‐Chao, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7sqi0b427utqu84f0pd7aug5da