Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase

T-cell-originated protein kinase (TOPK) is highly expressed in several cancer cells and promotes tumorigenesis and progression, and therefore, it is an important target for drug treatment of tumor. Pantoprazole (PPZ) was identified to be a TOPK inhibitor from FDA-approved drug database by structure...

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Detalles Bibliográficos
Autores principales: Zeng, Xiaoyu, Liu, Lin, Zheng, Mengzhu, Sun, Huimin, Xiao, Juanjuan, Lu, Tao, Huang, Guangqian, Chen, Pianpian, Zhang, Jianmin, Zhu, Feng, Li, Hua, Duan, Qiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008373/
https://www.ncbi.nlm.nih.gov/pubmed/26967058
http://dx.doi.org/10.18632/oncotarget.7984

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