Antitumor activity and inhibitory effects on cancer stem cell-like properties of Adeno-associated virus (AAV) -mediated Bmi-1 interference driven by Bmi-1 promoter for gastric cancer

Bmi-1 is aberrantly activated in various cancers and plays a vital role in maintaining the self-renewal of stem cells. Our previous research revealed that Bmi-1 was overexpressed in gastric cancer (GC) and it's overexpression was an independent negative prognostic factor, suggesting it can be a...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaowei, Guo, Weijian, Wang, Xiaofeng, Liu, Xinyang, Huang, Mingzhu, Gan, Lu, Cheng, Yufan, Li, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008396/
https://www.ncbi.nlm.nih.gov/pubmed/27009837
http://dx.doi.org/10.18632/oncotarget.8174

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