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Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) acts as a potential genetic modifier for Alzheimer's disease (AD). Previous reports identified that HMGCR rs3846662 polymorphism is associated with biosynthesis of cholesterol in AD pathology. In order to assess the involvement of the HMGCR p...

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Detalles Bibliográficos
Autores principales:	Chang, Xiao-Long, Tan, Lin, Tan, Meng-Shan, Wang, Hui-Fu, Tan, Chen-Chen, Zhang, Wei, Zheng, Zhan-Jie, Kong, Ling-Li, Wang, Zi-Xuan, Jiang, Teng, Yu, Jin-Tai, Tan, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008397/ https://www.ncbi.nlm.nih.gov/pubmed/27009838 http://dx.doi.org/10.18632/oncotarget.8176

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