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Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1
Epigenetic regulation by SIRT1, a multifaceted NAD(+)-dependent protein deacetylase, is one of the most common factors modulating cellular processes in a broad range of diseases, including prostate cancer (CaP). SIRT1 is over-expressed in CaP cells, however the associated mechanism is not well under...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008401/ https://www.ncbi.nlm.nih.gov/pubmed/26988912 http://dx.doi.org/10.18632/oncotarget.8061 |