Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins

We previously reported that the histone lysine methyltransferase SUV39H2, which is overexpressed in various types of human cancer, plays a critical role in the DNA repair after double strand breakage, and possesses oncogenic activity. Although its biological significance in tumorigenesis has been el...

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Detalles Bibliográficos
Autores principales: Piao, Lianhua, Nakakido, Makoto, Suzuki, Takehiro, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008405/
https://www.ncbi.nlm.nih.gov/pubmed/26988914
http://dx.doi.org/10.18632/oncotarget.8072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008405/
https://www.ncbi.nlm.nih.gov/pubmed/26988914
http://dx.doi.org/10.18632/oncotarget.8072

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